What is pain-relief medicine?

Pain-relief medicines are used as part of a strategy to manage short-term (acute) or long-term (chronic) pain. They work by targeting the cause of your pain or by reducing how your pain travels along the nerves to the brain.

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What are the different types of pain-relief medicines?

As everyone’s experience of pain is different, individuals need different ways to help manage their pain. There are also specific pain-relief options that suit some circumstances or health conditions.

You can buy some pain-relief medicines 'over-the-counter' (OTC). This means you don’t need a prescription from your doctor to access them. Others are only available with a doctor’s prescription.

Over-the-counter (OTC) medicines include:

paracetamol

non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, aspirin or diclofenac

gels and creams with medicines (such as NSAIDs and capsaicin) that are absorbed through your skin (topical medicines)

Your doctor may also prescribe a medicine, such as:

anticonvulsant medicines, such as pregabalin, gabapentin or carbamazepine

antidepressants, such as amitriptyline or duloxetine

opioids, for example codeine, morphine or tramadol

other types of medicine that treat the cause of your pain, such as muscle relaxants or corticosteroids

There are also many ways to manage pain that don’t involve medicines, such as:

stress management

meditation

exercise

Talk to your GP about the options or combinations that may be useful for you.

Over-the-counter (OTC) medicines

OTC medicines are medicines that you can buy without having a doctor’s prescription. Some types of OTC pain-relief medicine are available from a pharmacy and some shops. These are usually for mild-to-moderate pain.

There are 2 common types of OTC pain medicines:

Paracetamol is often recommended as the first medicine to try, if you have short-term pain.

Nonsteroidal anti-inflammatory drugs (NSAIDs) is a group of medicines that work by reducing swelling and inflammation, and relieving pain. These include aspirin, ibuprofen and diclofenac.

While OTC medicines are more easily accessed, they still carry risks. These medicines can sometimes cause unwanted side effects. If you take other medicines or substances, OTC pain-relief medicines can affect how your body responds to them. Your doctor or pharmacist can advise you on if it is safe to take OTC medicines for pain relief together with your other medicines.